The following dialogue box appears after clicking “Edit profile”:

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If the user is local, you can edit your own profile information:

An e-mail address is also displayed. However, it cannot be edited by the user. If it is necessary to change it, the application administrator must be contacted.

If the user is not local (account is from Active Directory or ADFS), the profile information is synced from remote directory and nothing can be changed, except preferred language.